Kodangala Subraya Chandrashekar, Santanu Saha and Prasanna Kodangala Subraya
Abstract:
The analgesic activity of the methanol extract of Phyllanthus lawii (MEPL) was investigated in Swiss albino mice with hot plate and acetic acid induced writhing models. The results suggested that MEPL possess potent analgesic activity. The MEPL produced a significant decrease in mice writhing induced by acetic acid suggesting peripheral analgesic activity and elevated mean basal reaction time in hot plate method suggesting central analgesic activity. The results are in agreement with its traditional use for pain treatment of P. lawii.
Keywords: Phyllanthus lawii, methanol extract, acetic acid induced, analgesic activity, swiss albino mice.
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